How do you treat Cystic Fibrosis?There are many different ways to treat cystic fibrosis. Some of them include: Airway clearanceCFTRAntibioticsLung transplantClinical TrialThe most common method is airway clearance, which loosens mucus from your lungs so it can be removed by coughing or hacking. This method is used for less severe cases of Cystic Fibrosis. There are also CFTR (cystic fibrosis transmembrane conductance regulator) Modulator Therapies are made to correct the function of defective CF proteins. These proteins regulate flow in fluids and sodium inside and outside the lungs. When the proteins work, there is effective movement of mucus out of the airways. When they don’t work, there becomes a clog which is a major concern.
Proteins can fail to work because mutations change protein building blocks in the CFTR protein. The result of this is the cell never reaches the cell membrane to transport chloride ions, which cause improper mucus movement out of the airway. You take these modulators in the form of 150mg tablets two to four times a day, depending on your weight, with some type of fattening food. For cystic fibrosis, there are a variety of antibiotics offered to help with different issues, such as helping clear airways and prevent infections. For some patients, when antibiotics are not successful, there is the option of a lung transplant.
It takes a long time to apply for a new lung but the process can be successful and improve quality of life. In terms of how scientists are working to cure this disease, there is ongoing research that is tested with clinical trials. There is a protocol trial that starts to determine if you are eligible, which includes:How many patients will participateWho is eligibleTests patients will get and how oftenWhat type of data collectedDetails about the treatment planClinical trials are randomized but test a group with varying severities of cystic fibrosis with new medicine, which may aid their treatment. New things are being learned about Cystic Fibrosis every day, so new clinical trials are conducted often to test new medicines.