Consistent 1.12 (95% CI: 1.03–1.21) for Hispanic mothers.

Consistent Occurrence estimates from the foundation
for determining the resources required for health care and education, as well
as for basic science and public health research. Study of widely extended
diseases among populations helps us to identify the reasons behind them and
also we can predict public health interventions. The plan of studies to
approximate the incidence of DS must be clearly stated to understand the
results.  Birth incidence or impulsive
and elective abortions can be focused by these studies. The previous would be
more efficient for studying the clinical features of DS, such as heart and
gastrointestinal defects, and for estimating healthcare needs, whereas the
latter would be more appropriate for providing information about probable
exposures linked with chromosome non disjunction. To approximate the birth
incidence of DS in U.S a large study was provided by the report of Canfield et
al. 2006. Active –case finding methods were used to obtained data from 11
birth inspection systems. All pregnancy outcomes, together with live births,
fetal deaths, impulsive and induced abortions and all gestational ages were
suitable. However, each active inspection system is different in their case
insertion criteria with respect to pregnancy outcome, gestational age and the
capability to determine parentally diagnosed cases from particular sources.
13.65 95% confidence intervals (CI): 13.22–14.09 per 10,000 live births, or 1/732
was the predictable maternal age-adjusted occurrence of DS based on the
inspection of 22% of the live births in the U.S. It means that out of 4 million
infants that born each year in U.S 5,400 have DS. Canfield et al. further
investigated differences in maternal-age adjusted occurrence rates among the
three major maternal racial/ethnic groups in the U.S.: non-Hispanic white,
non-Hispanic black and Hispanic. Compared with non-Hispanic white mothers, the
prevalence ratio was 0.77 (95% CI: 0.69–0.87) for non-Hispanic black mothers
and 1.12 (95% CI: 1.03–1.21) for Hispanic mothers. These differences are based
upon important technical issues related to parental records and impulsive
abortions, still birth and live birth. These diseases could also be influenced
by the socio economic and educational conditions in these three groups.
Khoshnood et al., 2004, 2006; Coory